Pathophysiology of Hemorrhage as It Relates to the Warfighter

Author:

Hinojosa-Laborde Carmen1ORCID,Hudson Ian L.1,Ross Evan1,Xiang Lusha1,Ryan Kathy L.1

Affiliation:

1. U.S. Army Institute of Surgical Research, JBSA Fort Sam Houston, San Antonio, Texas

Abstract

Saving lives of wounded military warfighters often depends on the ability to resolve or mitigate the pathophysiology of hemorrhage, specifically diminished oxygen delivery to vital organs that leads to multiorgan failure and death. However, caring for hemorrhaging patients on the battlefield presents unique challenges that extend beyond applying a tourniquet and giving a blood transfusion, especially when battlefield care must be provided for a prolonged period. This review describes these challenges and potential strategies for treating hemorrhage on the battlefield in a prolonged casualty care situation.

Funder

U.S. Army Medical Research and Development Command

Publisher

American Physiological Society

Subject

Physiology

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