Circadian Etiology of Type 2 Diabetes Mellitus-Reference-Cited by-同舟云学术

Circadian Etiology of Type 2 Diabetes Mellitus

Published:2018-03-01 Issue:2 Volume:33 Page:138-150
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Javeed Naureen¹,Matveyenko Aleksey V.¹²

Affiliation:

1. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota

2. Department of Medicine, Division of Endocrinology, Metabolism, Diabetes, and Nutrition, Mayo Clinic School of Medicine, Mayo Clinic, Rochester, Minnesota

Abstract

The epidemic of Type 2 diabetes mellitus necessitates development of novel therapeutic and preventative strategies to attenuate expansion of this debilitating disease. Evidence links the circadian system to various aspects of diabetes pathophysiology and treatment. The aim of this review will be to outline the rationale for therapeutic targeting of the circadian system in the treatment and prevention of Type 2 diabetes mellitus and consequent metabolic comorbidities.

Funder

NIH/NIDDK

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00003.2018

Reference175 articles.

1. Daily Fasting Blood Glucose Rhythm in Male Mice: A Role of the Circadian Clock in the Liver

2. CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function

3. Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver