New fACEs to the Renin-Angiotensin System-Reference-Cited by-同舟云学术

New fACEs to the Renin-Angiotensin System

Published:2005-04 Issue:2 Volume:20 Page:91-95
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Fleming Ingrid¹,Kohlstedt Karin¹,Busse Rudi¹

Affiliation:

1. Vascular Signaling Group, Institut für Kardiovaskuläre Physiologie, Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany

Abstract

Inhibition of the angiotensin-converting enzyme (ACE) protects against the progression of several cardiovascular diseases. Recent evidence suggests that some of the beneficial effects of ACE inhibitors can be attributed to the activation of a distinct ACE signaling cascade rather than to the changes in angiotensin II and bradykinin levels. Moreover, at least one other ACE homolog (ACE2) plays a significant role in the regulation of heart and kidney function.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00003.2005

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