Affiliation:
1. Department of Physiology, The David Geffen School of Medicine at the University of California-Los Angeles, Los Angeles, California 90095-1751
Abstract
SLC5 is an ancient gene family with 11 members in the human genome. These membrane proteins have diverse, multiple functions ranging from actively transporting solutes, ions, and water, to channeling water and urea, to sensing glucose in cholinergic neurons. Metabolic disorders have been identified that are associated with congenital mutations in two of the human genes.
Publisher
American Physiological Society
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