Skeletal Muscle Microvasculature: A Highly Dynamic Lifeline

Author:

Latroche Claire1234,Gitiaux Cyril1234,Chrétien Fabrice4,Desguerre Isabelle123,Mounier Rémi56,Chazaud Bénédicte12356

Affiliation:

1. Institut Cochin, INSERM U1016, Paris, France;

2. CNRS 8104, Paris, France;

3. Université Paris Descartes, Paris, France;

4. Institut Pasteur, Paris, France;

5. CGPhyMC, CNRS UMR5534, Villeurbanne, France; and

6. Université Claude Bernard Lyon1, Villeurbanne, France

Abstract

Skeletal muscle is highly irrigated by blood vessels. Beyond oxygen and nutrient supply, new vessel functions have been identified. This review presents vessel microanatomy and functions at tissue, cellular, and molecular levels. Mechanisms of vessel plasticity are described during skeletal muscle development and acute regeneration, and in physiological and pathological contexts.

Funder

French Ministery of Research

CNRS-APHP

FP7 Endostem

AFM-Téléthon (French Muscular Dystrophy Association)

Publisher

American Physiological Society

Subject

Physiology

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