First Encounter: How Pathogens Compromise Epithelial Transport-Reference-Cited by-同舟云学术

First Encounter: How Pathogens Compromise Epithelial Transport

Published:2004-10 Issue:5 Volume:19 Page:240-244
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Kunzelmann Karl¹,McMorran Brendan²

Affiliation:

1. Institut für Physiologie, Universität Regensburg, D-93053 Regensburg, Germany

2. Institute of Molecular Bioscience, The University of Queensland, St. Lucia, 4072 Queensland, Australia

Abstract

Pathogenic organisms trigger numerous signaling pathways that ultimately lead to drastic changes in physiological functions. Apart from altering structure and function of the epithelial tight junction barrier and activating inflammatory cascades, they induce changes in fluid and electrolyte transport. Pathogens do so by activating or by inhibiting ion channels and transporters, and the result might be to their benefit or to their disadvantage.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00015.2004

Reference48 articles.

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