Right Ventricular-Pulmonary Vascular Interactions

Author:

Tabima Diana M.1,Philip Jennifer L.12,Chesler Naomi C.1

Affiliation:

1. Department of Biomedical Engineering, University of Wisconsin-Madison College of Engineering, Madison, Wisconsin; and

2. Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin

Abstract

Accurate and comprehensive evaluation of right ventricular (RV)-pulmonary vascular (PV) interactions is critical to the assessment of cardiopulmonary function, dysfunction, and failure. Here, we review methods of quantifying RV-PV interactions and experimental results from clinical trials as well as large- and small-animal models based on pressure-volume analysis. We conclude by outlining critical gaps in knowledge that should drive future studies.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute (NHBLI)

Publisher

American Physiological Society

Subject

Physiology

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