A flexible carbon nanotube electrode array for acute in vivo EMG recordings

Author:

Pack Andrea R.12ORCID,Yan Jiaxi S.34ORCID,Pasquali Mateo4567,Sober Samuel J.2,Elemans Coen P. H.8ORCID

Affiliation:

1. Neuroscience Graduate Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, Georgia, United States

2. Department of Biology, Emory University, Atlanta, Georgia, United States

3. Department of Bioengineering, Rice University, Houston, Texas, United States

4. Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas, United States

5. Department of Chemistry, The Smalley Institute for Nanoscale Science and Technology, Rice University, Houston, Texas, United States

6. Department of Electrical and Computer Engineering, The Smalley Institute for Nanoscale Science and Technology, Rice University, Houston, Texas, United States

7. Department of Physics and Astronomy, Applied Physics Program, The Smalley Institute for Nanoscale Science and Technology, Rice University, Houston, Texas, United States

8. Department of Biology, University of Southern Denmark, Odense, Denmark

Abstract

We introduce a novel approach to record high-resolution EMG signals in small muscles using extremely strong and flexible carbon nanotube fibers (CNTFs). We test their functionality in songbird vocal muscles. Acute EMG recordings successfully yielded multiunit recordings with high SNR. Furthermore, they successfully isolated single-unit spike trains from CNTF recordings. CNTF electrodes have great potential for chronic EMG studies of small, deep muscles that demand high electrode flexibility and strength.

Funder

DOD | Air Force Office of Scientific Research

HHS | NIH | National Institute of Neurological Disorders and Stroke

HHS | NIH | National Institute on Drug Abuse

HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Science Foundation

Novo Nordisk Fonden

Welch Foundation

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

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