Assessing cerebellar-cortical connectivity using concurrent TMS-EEG: a feasibility study

Author:

Fernandez Lara1,Biabani Mana2ORCID,Do Michael1ORCID,Opie George M.3ORCID,Hill Aron T.1ORCID,Barham Michael P.1ORCID,Teo Wei-Peng4,Byrne Linda K.1ORCID,Rogasch Nigel C.25,Enticott Peter G.1ORCID

Affiliation:

1. Cognitive Neuroscience Unit, School of Psychology, Deakin University, Victoria, Australia

2. The Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Victoria, Australia

3. Discipline of Physiology, Adelaide Medical School, The University of Adelaide, Adelaide, Australia

4. Physical Education and Sports Science Academic Group, National Institute of Education, Nanyang Technical University, Singapore, 637616

5. Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia

Abstract

This is the first study to systematically assess the feasibility of obtaining TMS-evoked potentials from cerebellar stimulation with concurrent EEG. An innovative control condition using electrical stimulation was modified to mimic the sensory aspects of cerebellar stimulation with a double-cone coil, and a state-of-the art cleaning pipeline was trialled. The extent of artifact contamination in signals from stimulation of a cerebellar and an occipital/parietal control site using two TMS coil types was highlighted.

Funder

ARC Centre of Excellence in Cognition and its Disorders

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

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