Affiliation:
1. Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania
Abstract
Searching for a specific visual object requires our brain to compare the items in view with a remembered representation of the sought target to determine whether a target match is present. This comparison is thought to be implemented, in part, via the combination of top-down modulations reflecting target identity with feed-forward visual representations. However, it remains unclear whether top-down signals are integrated at a single locus within the ventral visual pathway (e.g., V4) or at multiple stages [e.g., both V4 and inferotemporal cortex (IT)]. To investigate, we recorded neural responses in V4 and IT as rhesus monkeys performed a task that required them to identify when a target object appeared across variation in position, size, and background context. We found nonvisual, task-specific signals in both V4 and IT. To evaluate whether V4 was the only locus for the integration of top-down signals, we evaluated several feed-forward accounts of processing from V4 to IT, including a model in which IT preferentially sampled from the best V4 units and a model that allowed for nonlinear IT computation. IT task-specific modulation was not accounted for by any of these feed-forward descriptions, suggesting that during object search, top-down signals are integrated directly within IT. NEW & NOTEWORTHY To find specific objects, the brain must integrate top-down, target-specific signals with visual information about objects in view. However, the exact route of this integration in the ventral visual pathway is unclear. In the first study to systematically compare V4 and inferotemporal cortex (IT) during an invariant object search task, we demonstrate that top-down signals found in IT cannot be described as being inherited from V4 but rather must be integrated directly within IT itself.
Funder
HHS | NIH | National Eye Institute
Simons Foundation
National Science Foundation
McKnight Foundation
Publisher
American Physiological Society
Subject
Physiology,General Neuroscience
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献