Stimulus predictability moderates the withdrawal strategy in response to repetitive noxious stimulation in humans-Reference-Cited by-同舟云学术

Stimulus predictability moderates the withdrawal strategy in response to repetitive noxious stimulation in humans

Published:2020-06-01 Issue:6 Volume:123 Page:2201-2208
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Jure Fabricio A.¹^ORCID,Arguissain Federico G.¹²^ORCID,Biurrun Manresa José A.²³,Graven-Nielsen Thomas²,Andersen Ole Kæseler¹²

Affiliation:

1. Integrative Neuroscience, SMI®, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark

2. Center for Neuroplasticity and Pain (CNAP), SMI®, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark

3. Centro de Investigaciones y Transferencia de Entre Ríos (CITER) CONICET-UNER, Entre Ríos, Argentina

Abstract

Innate defensive behaviors such as reflexes are found across all species, constituting preprogrammed responses to external threats that are not anticipated. Previous studies indicated that the excitability of the reflex arcs like spinal nociceptive withdrawal reflex (NWR) pathways in humans are modulated by several cognitive factors. This study assesses how the predictability of a threat affects the biomechanical pattern of the withdrawal response, showing that distal and proximal muscles are differentially modulated by descending control.

Funder

Danish National Research Foundation

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00028.2020

Reference73 articles.

1. Botulinum toxin A modifies nociceptive withdrawal reflex in subacute stroke patients

2. Expansion of nociceptive withdrawal reflex receptive fields in spinal cord injured humans

3. Electrophysiological and psychophysical quantification of temporal summation in the human nociceptive system

4. Sensitization in patients with painful knee osteoarthritis

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