Oscillatory entrainment mechanisms and anticipatory predictive processes in children with autism spectrum disorder

Author:

Beker Shlomit12ORCID,Foxe John J.123ORCID,Molholm Sophie1234ORCID

Affiliation:

1. Department of Pediatrics, The Cognitive Neurophysiology Laboratory, Albert Einstein College of Medicine, Bronx, New York

2. Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York

3. Department of Neuroscience, The Cognitive Neurophysiology Laboratory, The Ernest J. Del Monte Institute for Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York

4. Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York

Abstract

We examined behavioral and EEG indices of predictive processing in children with ASD to rhythmically predictable stimuli. Although behavioral measures of predictive processing and evoked neural responses were intact in the ASD group, neurophysiological measures of preparatory activity and entrainment were impaired. When sensory events are presented in a predictable temporal pattern, performance and neuronal responses in ASD may be governed more by the occurrence of the events themselves and less by their anticipated timing.

Funder

HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development

University of Rochester

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

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