1. Division of Orthodontics, Department of Human Development and Fostering, Meikai University School of Dentistry, Sakado, Saitama, Japan;
2. Division of Pharmacology, Department of Diagnostics and Therapeutics Science, Meikai University School of Dentistry, Sakado, Saitama, Japan; and
3. Meikai University Research Institute of Odontology, Saitama, Japan