Chronotropic and vasoactive properties of the gut bacterial short-chain fatty acids in larval zebrafish-Reference-Cited by-同舟云学术

Chronotropic and vasoactive properties of the gut bacterial short-chain fatty acids in larval zebrafish

Published:2024-06-01 Issue:6 Volume:56 Page:426-435
ISSN:1094-8341
Container-title:Physiological Genomics
language:en
Short-container-title:Physiological Genomics

Author:

Sree Kumar Hemaa¹²^ORCID,Wisner Alexander S.³⁴,Schiefer Isaac T.³⁴,Alviter Plata Adriana¹,Zubcevic Jasenka¹^ORCID

Affiliation:

1. Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, United States

2. Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, United States

3. Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, Ohio, United States

4. Center for Drug Design and Development, University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, Ohio, United States

Abstract

We highlight the presence of a core gut microbiota and demonstrate in vivo short-chain fatty acid production in adult zebrafish. In addition, we show cardio-beneficial vasoactive and chronotropic properties of butyrate, and chronotropic properties of acetate in anesthetized zebrafish larvae.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

UT | College of Medicine and Life Sciences, University of Toledo

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/physiolgenomics.00013.2024

Reference89 articles.

1. Zebrafish as an animal model for biomedical research

2. The zebrafish reference genome sequence and its relationship to the human genome

3. Zebrafish as a model to study cardiac development and human cardiac disease

4. The use of microangiography in detecting aberrant vasculature in zebrafish embryos exposed to cadmium

5. Visualizing Vascular Networks in Zebrafish: An Introduction to Microangiography

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Intestinal serotonergic vagal signaling as a mediator of microbiota-induced hypertension;2024-07-22