Knockdown of deoxythymidylate kinase suppresses progression and epithelial-mesenchymal-transition of lung adenocarcinoma via STAT3 signaling-Reference-Cited by-同舟云学术

Knockdown of deoxythymidylate kinase suppresses progression and epithelial-mesenchymal-transition of lung adenocarcinoma via STAT3 signaling

Published:2023-05-01 Issue:5 Volume:55 Page:213-221
ISSN:1094-8341
Container-title:Physiological Genomics
language:en
Short-container-title:Physiological Genomics

Author:

Yu Fengqiang¹²^ORCID,Chen Yanxun³,Qiu Ruiqin¹²,Lin Nanlong¹²,Yin Yinhe³,Zhuo Yi¹²,Lin Jianbo¹²,Lai Fancai¹²

Affiliation:

1. Department of Thoracic Surgery, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China

2. Department of Thoracic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China

3. Department of Thoracic Surgery, Quangang District Hospital, Quanzhou, China

Abstract

DTYMK plays an important role in progression of LUAD through the STAT3 signaling pathway. YMU1 may serve as a novel drug to suppress the development of LUAD.

Funder

Fujian Provincial Health Commission

National Natural Science Foundation of China

Publisher

American Physiological Society

Subject

Genetics,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/physiolgenomics.00001.2023

Reference29 articles.

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3. Human dTMP Kinase: Gene Expression and Enzymatic Activity Coinciding with Cell Cycle Progression and Cell Growth

4. Insights into product release dynamics through structural analyses of thymidylate kinase

5. Tumor Cells Require Thymidylate Kinase to Prevent dUTP Incorporation during DNA Repair

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