The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females

Author:

Knowles Olivia E.1ORCID,Soria Megan2,Saner Nicholas J.3,Trewin Adam J.1ORCID,Alexander Sarah E.4ORCID,Roberts Spencer S. H.1,Hiam Danielle1,Garnham Andrew P.1ORCID,Drinkwater Eric J.1,Aisbett Brad1,Lamon Séverine1ORCID

Affiliation:

1. Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia

2. School of Life and Environmental Sciences, Deakin University, Geelong, Victoria, Australia

3. Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia

4. Cardiometabolic Health and Exercise Physiology, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

Abstract

This study investigated the effect of nine nights of sleep restriction, with repeated resistance exercise sessions, on the skeletal muscle transcriptome of young, trained females. Sleep restriction and resistance exercise interacted to alter the enrichment of skeletal muscle transcriptomic pathways in young, resistance-trained females. Performing exercise when sleep restricted may not provide the same adaptive response for individuals as if they were fully rested.

Publisher

American Physiological Society

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