Altered functional connectivity in the hippocampal and striatal systems after motor sequence learning consolidation in medial temporal lobe epilepsy individuals-Reference-Cited by-同舟云学术

Altered functional connectivity in the hippocampal and striatal systems after motor sequence learning consolidation in medial temporal lobe epilepsy individuals

Published:2024-02-01 Issue:2 Volume:131 Page:294-303
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Zhang Xiaotong¹,Feng Yanyun²,Chen Zhuoming¹,Long Jinyi³⁴^ORCID

Affiliation:

1. Department of Rehabilitation Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China

2. Department of Radiology, The First People’s Hospital of Foshan, Foshan, Guangdong, China

3. College of Information Science and Technology, Jinan University, Guangzhou, Guangdong, China

4. Pazhou Lab, Guangzhou, Guangdong, China

Abstract

Motor sequence learning (MSL) relies on both the hippocampal and striatal systems, but whether functional performance is altered after MSL consolidation when the hippocampus is impaired remains unknown. Our results indicated that whereas the main effect of consolidation was observed in the hippocampus-related functional connection in the healthy control (HC) group, it was only evident in the striatum-related functional loop in the left medial temporal lobe epilepsy (LmTLE) group.

Funder

guangzhouKey Science & Technology Brainstorm Project of Guangzhou

MOE | Fundamental Research Funds for the Central Universities

Guangdong Provincial Key Laboratory of Traditional Chinese Medicine

Science and Technology Planning Project of Guangdong Province

MOST | National Key Research and Development Program of China

MOST | National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00376.2023

Reference44 articles.

1. Both the Hippocampus and Striatum Are Involved in Consolidation of Motor Sequence Memory

2. Contributions of the basal ganglia and functionally related brain structures to motor learning

3. Current concepts in procedural consolidation

4. The memory function of sleep

5. Hippocampal and striatal responses during motor learning are modulated by prefrontal cortex stimulation