Affiliation:
1. Department of Kinesiology, University of California, Los Angeles90024-1527.
Abstract
An in vitro brain stem-spinal cord preparation from last trimester (E13-E21) fetal rats, which generates rhythmic respiratory and locomotor patterns, is described. These coordinated motor patterns emerge at stages E17-E18. Synchronous rhythmic motor activity, not clearly characterized as respiratory or locomotor, can occur as early as E13. With this preparation, it is now possible to study the ontogenesis of circuits and cellular mechanisms underlying these critical movements.
Publisher
American Physiological Society
Subject
Physiology,General Neuroscience
Cited by
131 articles.
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