CD8<sup>+</sup> T-cell metabolism is related to cerebrovascular reactivity in middle-aged adults-Reference-Cited by-同舟云学术

CD8⁺ T-cell metabolism is related to cerebrovascular reactivity in middle-aged adults

Published:2024-05-01 Issue:5 Volume:326 Page:R416-R426
ISSN:0363-6119
Container-title:American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
language:en
Short-container-title:American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Author:

DeConne Theodore M.¹^ORCID,Fancher Ibra S.²^ORCID,Edwards David G.²^ORCID,Trott Daniel W.³^ORCID,Martens Christopher R.²^ORCID

Affiliation:

1. Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States

2. Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States

3. Department of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States

Abstract

Peripheral T-cell metabolism is related to in vivo cerebrovascular reactivity in humans. Higher glycolytic metabolism in CD8+ T cells was associated with lower cerebrovascular reactivity to a breath-hold in middle-aged adults, which is possibly reflective of a more proinflammatory state in midlife.

Funder

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpregu.00267.2023

Reference68 articles.

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