Single and 7-day handgrip and squat exercise prevents endothelial ischemia-reperfusion injury in individuals with cardiovascular disease risk factors-Reference-Cited by-同舟云学术

Single and 7-day handgrip and squat exercise prevents endothelial ischemia-reperfusion injury in individuals with cardiovascular disease risk factors

Published:2024-01-01 Issue:1 Volume:326 Page:R79-R87
ISSN:0363-6119
Container-title:American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
language:en
Short-container-title:American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Author:

Somani Yasina B.¹²³^ORCID,Boidin Maxime¹⁴³,Peggen Mandy A. G.⁵^ORCID,Wanders Iris⁵,Proctor David N.⁶^ORCID,Low David A.¹^ORCID,Jones Helen¹^ORCID,Lip Gregory Y. H.³⁷^ORCID,Thijssen Dick H. J.¹⁵³

Affiliation:

1. Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom

2. Department of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom

3. Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom

4. Department of Sport and Exercise Sciences, Institute of Sport, Manchester Metropolitan University, Manchester, United Kingdom

5. Department of Medical Biosciences, Radboud University Medical Centre, Nijmegen, The Netherlands

6. Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, United States

7. Department of Clinical Medicine, Danish Center for Clinical Health Services, Aalborg University, Aalborg, Denmark

Abstract

We show that single bouts of dynamic handgrip and squat exercise provide remote protection against endothelial ischemia-reperfusion (IR)-induced injury in individuals with cardiovascular disease (CVD) risk factors, with 1-wk daily, home-based exercise preserving these effects for up to 24 h following the last exercise bout.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpregu.00168.2023

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