IBS randomized study: FODMAPs alter bile acids, phenolic- and tryptophan metabolites, while gluten modifies lipids-Reference-Cited by-同舟云学术

IBS randomized study: FODMAPs alter bile acids, phenolic- and tryptophan metabolites, while gluten modifies lipids

Published:2023-09-01 Issue:3 Volume:325 Page:R248-R259
ISSN:0363-6119
Container-title:American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
language:en
Short-container-title:American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Author:

Nordin Elise¹^ORCID,Hellström Per M.²^ORCID,Vuong Eddie¹,Ribbenstedt Anton¹,Brunius Carl¹,Landberg Rikard¹

Affiliation:

1. Department of Biology and Biological Engineering, Food and Nutrition Science, Chalmers University of Technology, Gothenburg, Sweden

2. Department of Medical Sciences, Gastroenterology/Hepatology, Uppsala University, Uppsala, Sweden

Abstract

In irritable bowel syndrome (IBS), fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs) affected microbial-derived metabolites relating to positive health outcomes such as reduced risk of colon cancer, inflammation, and type 2 diabetes, as shown in previous studies. The minor IBS symptom induction by FODMAP intake must be weighed against the positive health aspects of FODMAP consumption. Gluten affected lipids weakly with no association to IBS severity.

Funder

Svenska Forskningsrådet Formas

Vetenskapsrådet

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpregu.00016.2023

Reference100 articles.

1. Bowel Disorders

2. Pathophysiology of irritable bowel syndrome