Probiotic and high-fat diet: effects on pain assessment, body composition, and cytokines in male and female adolescent and adult rats-Reference-Cited by-同舟云学术

Probiotic and high-fat diet: effects on pain assessment, body composition, and cytokines in male and female adolescent and adult rats

Published:2024-08-01 Issue:2 Volume:327 Page:R123-R132
ISSN:0363-6119
Container-title:American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
language:en
Short-container-title:American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Author:

Raff Hershel¹²³⁴^ORCID,Hainsworth Keri R.⁵⁶^ORCID,Woyach Victoria L.⁵⁷,Weihrauch Dorothee⁵⁷,Wang Xuemeng⁸^ORCID,Dean Caron⁵⁷^ORCID

Affiliation:

1. Division of Endocrinology and Molecular Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, United States

2. Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States

3. Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States

4. Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin, United States

5. Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States

6. Jane B. Pettit Pain and Headache Center, Children’s Wisconsin, Milwaukee, Wisconsin, United States

7. Research Division, Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin, United States

8. Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Abstract

A single-strain probiotic (Lp299v) had a wide range of inhibiting effects on most proinflammatory cytokines (especially IL12p70) measured in this high-fat diet rat model of mild obesity. The positive effect of probiotic on leptin in female adolescent rats is intriguing and worthy of exploration.

Funder

Advancing a Healthier Wisconsin Endowment

U.S. Department of Veterans Affairs

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpregu.00082.2024

Reference80 articles.

1. Not small adults: the emerging role of pediatric pain services

2. The epidemiology of chronic pain in children and adolescents revisited: A systematic review

3. Reports of Chronic Pain in Childhood and Adolescence Among Patients at a Tertiary Care Pain Clinic

4. Effect of environment on the long-term consequences of chronic pain

5. The importance of psychosocial influences on chronic pain