Affiliation:
1. Department of Physiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Abstract
The present study demonstrated differential light responsiveness of the rising and falling phases of nocturnal melatonin secretion in human subjects exposed to artificial long (LD 16:8) and short days (LD 8:16) and suggested the involvement of different oscillators under these phases. The findings well mimicked the seasonality of the circadian rhythms in nature and consisted with the evening/morning dual oscillator hypothesis proposed originally for nocturnal rodents, providing a new concept for the human circadian system.
Funder
MEXT | Japan Society for the Promotion of Science
Publisher
American Physiological Society
Subject
Physiology (medical),Physiology
Cited by
1 articles.
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1. Two oscillatory components detected by forced splitting of the sleep-wake cycle in humans;American Journal of Physiology-Regulatory, Integrative and Comparative Physiology;2024-01-01