Body fluids and electrolytes after prolonged cardiopulmonary bypass

Author:

Brinsfield Dorothy1,Hopf M. A.1,Mayer S. E.1,Galletti P. M.1

Affiliation:

1. Departments of Physiology and Pediatrics, Emory University, Atlanta, Georgia

Abstract

Fluid and electrolyte balance was studied in 21 dogs after partial heart-lung bypass of 10 hr duration. Water retention was demonstrated by an increase in body weight and total body water, primarily due to an increase in extracellular fluid. Electrolyte retention was suggested by an increase in total extracellular sodium, potassium, and chloride. Urinary output was relatively normal but a progressive drop in urinary specific gravity was observed during bypass. Blood pH remained essentially unchanged. However, an increase in plasma lactate and a decrease in plasma bicarbonate suggested some degree of hypoxia and metabolic acidosis at the cellular level. Altered hormonal regulation of sodium and water excretion, hemolysis secondary to blood trauma, and the exchange of intracellular potassium for extracellular hydrogen ions were considered possible explanation for the fluid and electrolyte changes observed. assisted circulation; heart-lung bypass; acid-base balance; fluid balance; extracorporeal circulation; electrolyte changes with partial bypass; membrane oxygenator; disc oxygenator; bubble oxygenator Submitted on June 20, 1963

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Extracorporeal Membrane Oxygenation in the Treatment of Respiratory Failure—A Review;Anaesthesia and Intensive Care;1977-05

2. Techniques of Extended Perfusion Using a Membrane Lung;The Annals of Thoracic Surgery;1971-11

3. Experimental heart-lung bypass and assisted circulation;Progress in Cardiovascular Diseases;1969-01

4. Prolonged partial extracorporeal perfusion;American Heart Journal;1968-04

5. Partieller extrakorporaler Kreislauf im Tierversuch;Langenbecks Archiv f�r Klinische Chirurgie;1967-12

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