A nonthrombogenic diffusion membrane for continuous in vivo measurement of blood gases by mass spectrometry

Author:

Brantigen J. W.1,Gott V. L.1,Vestal M. L.1,Fergusson G. J.1,Johnston W. H.1

Affiliation:

1. Page 427: T. Uzawa and D. G. Ashbaugh. “Continuous positive-pressure breathing in acute hemorrhagic pulmonary edema”" Page 428: in column 1, paragraph 2, the second sentence should read: Acute hemorrhagic edema of the lungs was then produced by injecting 0.06 g/kg of oleic acid into the right ventricle (3).

Abstract

A heparinized silicone rubber diffusion membrane covering a 22-gauge stainless steel intravascular cannula allows continuous in vivo measurement of blood gas tensions by mass spectrometry in an unheparinized animal or patient. This system has been tested in the aortas of a series of five dogs for periods up to 24 hr, and nonheparinized controls have been used in two dogs. The controls showed evidence of membrane coagulation, but the heparinized membranes were non-thrombogenic and provided quantitatively accurate measurements of Po2 and Pco2 throughout. nonthrombogenic materials; blood gas tensions; oxygen; carbon dioxide; monitoring devices Submitted on July 18, 1969

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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