A new apparatus for the accurate measurement of airway resistance in infancy

Abstract

A new heated rebreathing system has been developed for the measurement of thoracic gas volume (TGV) and airway resistance (Raw) in infants by the plethysmographic technique. The apparatus has a linear response to flow rates between 0–160 ml-s-1, a dead space of 12 ml and a resistance of 5 cmH2O–1–1-S-1 at a flow rate of 60 ml-s-1. The inclusion of pneumatically operated valves in the apparatus is a major improvement over previous methods of occlusion for TGV measurements. The infant is allowed to rebreathe saturated gas at body temperature through the heated system, thus overcoming a potential source of error when measuring Raw in infants. Using this apparatus, the average coefficient of variation was 3.7% for TGV and 5.9% for Raw.