Effect of cardiac denervation on the maximal capacity for exercise in the racing greyhound

Author:

Donald David E.1,Milburn Sidney E.1,Shepherd John T.1

Affiliation:

1. Sections of Surgical Research and Physiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, and Elk Point, South Dakota

Abstract

Ten consecutive time trials were run at 2-day intervals by six racing greyhounds over a 5/16-mile track. Cardiac denervation was then performed on four dogs, and a sham operation that included removal of the pericardium was performed on two dogs. After cardiac denervation, one dog died and another was rejected from the study because of a massive intrathoracic hemorrhage. The time trials were repeated with the addition of telemetry of the heart rate in the four survivors. There was no significant difference between mean preoperative and postoperative race times in the control group. The mean postoperative running speeds of 33.6 and 33.3 mph in the denervated group, although representing a significant slowing of 1.1 and of 2.1 mph, respectively, from preoperative values, indicate the adequate manner in which the denervated heart meets the circulatory demands of maximal running effort. cardiac output; heart rate and exercise Submitted on March 11, 1964

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Cited by 69 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Limits to the Evidence that DNA Sequence Differences Contribute to Variability in Fitness and Trainability;Medicine & Science in Sports & Exercise;2019-08

2. Biological Reductionism versus Redundancy in a Degenerate World;Perspectives in Biology and Medicine;2018

3. Physiological Redundancy and the Integrative Responses to Exercise;Cold Spring Harbor Perspectives in Medicine;2017-05-10

4. Feedback control indirect response models;Journal of Pharmacokinetics and Pharmacodynamics;2016-07-09

5. Feedback Control Indirect Response Models;Systems Pharmacology and Pharmacodynamics;2016

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3