Author:
De Wilde R.,Clement J.,Hellemans J. M.,Decramer M.,Demedts M.,Boving R.,Van de Woestijne K. P.
Abstract
A model of the elasticity of the human lung has been developed to evaluate the relative importance of the characteristics of the lung parenchyma, of thorax configuration, and of gravity on the vertical gradients of pleural pressure and regional volumes, and on the linear displacements of lung tissue, of various lung volumes. The predictions of the model are compared with available experimental data. It is suggested that the bulk elasticity modulus of the human lung is high with respect to that of canine lungs, that the shearing forces are low ("effective" Poison's ratio of about 0.4-0.45), and that the variations of regional pleural pressures and volumes during deflation are determined primarily by the interaction between lung weight and changes in thorax configuration.
Publisher
American Physiological Society
Subject
Physiology (medical),Physiology
Cited by
26 articles.
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