Microvascular permeability, ultrafiltration, and restricted diffusion

Author:

Michel C. C.

Abstract

This essay looks at the historical significance of two APS classic papers that are freely available online: Pappenheimer JR and Soto-Rivera A. Effective osmotic pressure of the plasma proteins and other quantities associated with the capillary circulation in the hindlimbs of cats and dogs. Am J Physiol 152: 471–491, 1948 ( http://ajplegacy.physiology.org/cgi/reprint/152/3/471 ). Pappenheimer JR, Renkin EM, and Borrero LM. Filtration, diffusion and molecular sieving through peripheral capillary membranes: a contribution to the pore theory of capillary permeability. Am J Physiol 167: 13–46, 1951 ( http://ajplegacy.physiology.org/cgi/reprint/167/1/13 ).

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Reference12 articles.

1. INTERCELLULAR CEMENT AND CAPILLARY PERMEABILITY

2. CurryFE. Mechanics and thermodynamics of transcapillary exchange. In: Handbook of Physiology. The Cardiovascular System. Microcirculation. Bethesda, MD: Am Physiol Soc. 1984, sect. 2, vol. IV, pt. 1, chapt. 8, p. 309–374.

3. Starling: the formulation of his hypothesis of microvascular fluid exchange and its significance after 100 years

4. PappenheimerJR. Osmotic reflection coefficients in capillary membranes. In: Capillary Permeability: Transfer of Molecules and Ions Between Capillary Blood and Tissue, edited by Crone C and Lassen NA. Copenhagen, Denmark: Munksgaard, 1970, p. 278–286.

5. PappenheimerJR, Renkin EM, and Borrero LM. Filtration, diffusion and molecular sieving through peripheral capillary membranes: a contribution to the pore theory of capillary permeability. Am J Physiol 167: 13–46, 1951.

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