Muscle, liver, and pancreas: Three Musketeers fighting to control glycemia

Author:

Klip Amira,Vranic Mladen

Abstract

This essay examines the historical significance of two APS classic papers that are freely available on line: Wall JS, Steele R, de Bodo RC, and Altszuler N. Effect of insulin on utilization and production of circulating glucose. Am J Physiol 189: 43–50, 1957. ( http://ajplegacy.physiology.org/cgi/reprint/189/1/43 ) DeFronzo RA, Tobin JD, and Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol Endocrinol Metab Gastroinstest Physiol 6: E214–E223, 1979. ( http://ajpgi.physiology.org/cgi/reprint/237/3/G214 )

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology,Endocrinology, Diabetes and Metabolism

Reference16 articles.

1. Altszuler N. Modification of the effects of insulin by hormonal factors. In: Handbook of Experimental Pharmacology. New York: Springer-Verlag, 1975, vol. 32, no. 2, p. 536–567.

2. Andres R, Swerdloff R, Pozefsky T, and Coleman D. Manual feedback technique for the control of blood glucose concentration. In: Automation in Analytical Chemistry, edited by Skeggs LT Jr. New York: Mediad, 1966, p. 486–491.

3. Armstrong DT, Steele R, Altszuler N, Dunn A, Bishop JS, and de Bodo RC. Regulation of plasma free fatty acid turnover. Am J Physiol 201: 9–15, 1961.

4. Assessment of Insulin Sensitivityin Vivo*

5. Glucoregulatory responses in normal and diabetic dogs recorded by a new tracer method

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