Abstract
The phagocyte enzyme NADPH oxidase generates superoxide essential for antimicrobial defense;its genetic defects cause the immunodeficiency disorder chronic granulomatous disease. B lymphocytes and certain other nonphagocytes also express NADPH oxidase. Molecular approaches allow new ways to study the enzyme and promise to uncover why nonphagocytic cells express NADPH oxidase.
Publisher
American Physiological Society
Cited by
2 articles.
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