Affiliation:
1. J. H. Sellin is Professor of Medicine and Director of the Division of Gastroenterology at the University of Texas Medical School at Houston, PO Box 20708, Houston, TX 77225, USA.
Abstract
Short-chain fatty acids are the predominant luminal anions in the colon (>75 mM) and thus create a rather unique environment for transporting epithelium. The colon absorbs short-chain fatty acids, either by diffusion of the protonated species across the apical membrane or by an anion exchange process with bicarbonate. Additionally, short-chain fatty acids modulate Na absorption, Cl secretion, intracellular pH, and cell volume.
Publisher
American Physiological Society
Cited by
10 articles.
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