Stimulation of Glucose Transport by Hypoxia: Signals and Mechanisms-Reference-Cited by-同舟云学术

Stimulation of Glucose Transport by Hypoxia: Signals and Mechanisms

Published:1999-06 Issue:3 Volume:14 Page:105-110
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Behrooz Alireza¹,Ismail-Beigi Faramarz¹

Affiliation:

1. A. Behrooz and F. Ismail-Beigi are in the Departments of Molecular Biology and Microbiology, Medicine, and Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106–4951, USA.

Abstract

Glucose transport is acutely stimulated by hypoxia through enhanced GLUT-1 and GLUT-4 glucose transporter function. GLUT-1 expression is also stimulated by hypoxia or azide. Moreover, hypoxia per se, acting through hypoxia-inducible factor 1, enhances GLUT-1 transcription. GLUT-1 is the first gene whose transcription is dually stimulated in response to hypoxia and inhibition of oxidative phosphorylation.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiologyonline.1999.14.3.105

Reference15 articles.

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