Affiliation:
1. Michael Bliss is Professor of History at the University of Toronto, Toronto M5S 1A3, Canada.
Abstract
The discovery of insulin is commonly thought to be the result of a single brilliant idea of a young Canadian physician. The reality is far more complex, and careful historical research has revealed formidable scientific and human complications. Examination of relevant documents and laboratory notebooks has made it possible to reconstruct a complete history of the discovery, including the day-to-day experimental work with its progress and failures, and in the end to pinpoint the contributions that led to success. These events did not develop in peaceful harmony; there were incriminations and dramatic personality clashes.
Publisher
American Physiological Society
Cited by
7 articles.
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1. Evolution of biosynthetic human insulin and its analogues for diabetes management;Advances in Protein Chemistry and Structural Biology;2024
2. Insulin's centenary: the birth of an idea;The Lancet Diabetes & Endocrinology;2020-12
3. Insulin's discovery: New insights on its ninetieth birthday;Diabetes/Metabolism Research and Reviews;2012-05
4. Crataegi folium cum flore;Phytopharmaka in Forschung und klinischer Anwendung;1995
5. The Effect of Prostacyclin Analogs on Vascular K Channels;Ion Flux in Pulmonary Vascular Control;1993