Affiliation:
1. F. Grassi and F. Eusebi are at the Istituto Pasteur-Fondazione Cenci Bolognetti and Dipartimento di Medicina Sperimentale e Patologia, Università di Roma “La Sapienza,” Italy.
Abstract
In developing muscles in vivo and in vitro, the acetylcholine receptor γ-subunit exists in two splice variants, conferring different single-channel open durations (τop) to reconstituted receptors. In mouse muscles, τop changes around birth, possibly as receptors incorporate either variant of γ-subunit. This might be relevant to the concomitant maturation of muscle innervation.
Publisher
American Physiological Society