Neuroprotection and Angiogenesis: Dual Role of Erythropoietin in Brain Ischemia-Reference-Cited by-同舟云学术

Neuroprotection and Angiogenesis: Dual Role of Erythropoietin in Brain Ischemia

Published:2000-10 Issue:5 Volume:15 Page:225-229
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Marti Hugo H.¹,Bernaudin Myriam¹,Petit Edwige¹,Bauer Christian¹

Affiliation:

1. H. H. Marti is at the Max-Planck-Institut für Physiologische und Klinische Forschung, W. G. Kerckhoff-Institut, Abteilung Molekulare Zellbiologie, Parkstrasse 1, D-61231 Bad Nauheim, Germany. M. Bernaudin and E. Petit are at l'Université de Caen, UMR 6551-CNRS, IFR47-Neuro-Imagerie Fonctionelle, Bd. Henri Becquerel, BP 5229, F-14074 Caen cedex, France. C. Bauer is at the Physiologisches Institut, Universität Zürich-Irchel, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

Abstract

Erythropoietin, originally defined as an erythroid growth factor, is upregulated in the brain under conditions of hypoxia. So far, two functions have been identified for this locally produced cytokine: a direct protective effect on neuronal cells during cerebral ischemia and an indirect protection of brain tissue that could be provided by promoting brain vessel growth.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiologyonline.2000.15.5.225

Reference15 articles.

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5. Ischemic Cell Death in Brain Neurons

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