Affiliation:
1. Department of Biochemistry, University of Zurich, CH-8057 Zurich, Switzerland
Abstract
Induced fit explains why biomolecules can bind together even if they are not optimized for binding. However, induced fit can lead to a kinetic bottleneck and does not describe every interaction in the absence of prior complementarity. Preselection of a fitting conformer is an alternative to induced fit.
Publisher
American Physiological Society
Cited by
47 articles.
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