Alpha-ketoglutarate is required for chronic hypoxia-induced cardiac remodeling-Reference-Cited by-同舟云学术

Alpha-ketoglutarate is required for chronic hypoxia-induced cardiac remodeling

Published:2024-09-01 Issue:3 Volume:327 Page:C728-C736
ISSN:0363-6143
Container-title:American Journal of Physiology-Cell Physiology
language:en
Short-container-title:American Journal of Physiology-Cell Physiology

Author:

Tang Daishi¹^ORCID,Gu Yong¹,Chen Shasha²,Niu Tong³,Zhu Jin’ao²,Liu Panpan⁴,Ding Mingge⁵,Guo Yanjie⁴

Affiliation:

1. Digestive System Department, Shaanxi Provincial Crops Hospital of Chinese People's Armed Police Force, Xi'an, People’s Republic of China

2. The Second Clinical School of Medicine, Shaanxi University of Chinese Medicine, Xianyang, People’s Republic of China

3. Department of Hematology, Xi'an Daxing Hospital, Xi'an, People’s Republic of China

4. Department of Cardiology, Xi’an International Medical Center Hospital, Northwest University, Xi'an, People’s Republic of China

5. Department of Geriatrics Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People’s Republic of China

Abstract

We reported that alpha-ketoglutarate (α-KG) is indispensable for chronic hypoxia (CH)-induced cardiac remodeling, which builds the bridge between metabolic intermediates and cardiac remodeling.

Funder

陕西省科学技术厅 | Natural Science Basic Research Program of Shaanxi Province

MOST | National Natural Science Foundation of China

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpcell.00257.2024

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