1. School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences, The University of Nottingham, Sutton Bonington Campus, Leicestershire, United Kingdom;
2. Medical Research Council-Arthritis Research UK Centre for Musculoskeletal Ageing Research, Nottingham, United Kingdom;
3. Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, Arthritis Research UK Pain Centre, Queen's Medical Centre, Nottingham, United Kingdom; and
4. Center of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical Research Center (KFMRC), King AbdulAziz University, Jeddah, Kingdom of Saudi Arabia