Affiliation:
1. Department of Histology and Embryology, Croatian Institute for Brain Research, University of Zagreb School of Medicine, Zagreb, Croatia
Abstract
Stroke is one of the leading causes of mortality and the leading cause of long-term disability worldwide. Although cognitive impairment is a common consequence of stroke, the underlying pathophysiological processes that lead to it are still poorly understood. Recently, more studies have shown evidence of the involvement of diabetes in producing a chronic neuroinflammatory state, which ultimately alters the recovery of function and cognition after stroke. To better understand the impact of diabetes on poststroke recovery, here we highlight the recent insights on the role of diabetes in neuroinflammation, especially regarding its effect on microglial function, and the emerging data on the involvement of kinins in both diabetes and neuroinflammation.
Funder
EU ESIF European Regional Development Fund
Hrvatska Zaklada za Znanost
Publisher
American Physiological Society
Cited by
7 articles.
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