S100b treatment overcomes RAGE signaling deficits in myoblasts on advanced glycation end-product cross-linked collagen and promotes myogenic differentiation-Reference-Cited by-同舟云学术

S100b treatment overcomes RAGE signaling deficits in myoblasts on advanced glycation end-product cross-linked collagen and promotes myogenic differentiation

Published:2024-04-01 Issue:4 Volume:326 Page:C1080-C1093
ISSN:0363-6143
Container-title:American Journal of Physiology-Cell Physiology
language:en
Short-container-title:American Journal of Physiology-Cell Physiology

Author:

Olson Lucas C.¹²,Nguyen Tri¹,Sabalewski Eleanor L.¹,Puetzer Jennifer L.¹³,Schwartz Zvi¹⁴,McClure Michael J.¹³^ORCID

Affiliation:

1. Department of Biomedical Engineering, College of Engineering, Virginia Commonwealth University, Richmond, Virginia, United States

2. Department of Gerontology, College of Health Professionals, Virginia Commonwealth University, Richmond, Virginia, United States

3. Department of Orthopaedic Surgery, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, United States

4. Department of Periodontics, School of Dentistry, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

Abstract

Collagen cross-linked by advanced glycation end-products (AGEs) induced myoblast proliferation but prevented differentiation, myotube formation, and RAGE upregulation. RAGE inhibition occluded AGE-induced myoblast proliferation, while the delivery of S100b, a RAGE ligand, recovered fusion deficits.

Funder

MTF Biologics

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpcell.00502.2023

Reference56 articles.

1. An overview of sarcopenia: facts and numbers on prevalence and clinical impact

2. SATELLITE CELL OF SKELETAL MUSCLE FIBERS

3. Satellite-like cells contribute to pax7 -dependent skeletal muscle repair in adult zebrafish

4. The molecular regulation of myogenesis

5. Building Muscle: Molecular Regulation of Myogenesis

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