Role of glycolysis in the development of atherosclerosis-Reference-Cited by-同舟云学术

Role of glycolysis in the development of atherosclerosis

Published:2022-08-01 Issue:2 Volume:323 Page:C617-C629
ISSN:0363-6143
Container-title:American Journal of Physiology-Cell Physiology
language:en
Short-container-title:American Journal of Physiology-Cell Physiology

Author:

Li Lanfang¹^ORCID,Wang Min¹,Ma Qiuxiao²,Ye Jingxue¹,Sun Guibo¹

Affiliation:

1. Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China

2. Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China

Abstract

Atherosclerosis is a chronic inflammatory vascular disease associated with endothelial dysfunction, inflammation, and atherosclerotic plaque formation. Glycolysis is a conservative and rigorous biological process that decomposes glucose into pyruvate. Its function is to provide the body with energy and intermediate products required for life activities. However, abnormalities in glycolysis flux during the progression of atherosclerosis accelerate the disease progression. Herein, we review the role of glycolysis in the development of atherosclerosis to provide new ideas for devising novel antiatherosclerosis strategies.

Funder

National Natural Science Foundation of China

Science and Technology Innovation Project of China Academy of Chinese Medical Sciences

CAMS | Chinese Academy of Medical Sciences Initiative for Innovative Medicine

Publisher

American Physiological Society

Subject

Cell Biology,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpcell.00218.2022

Reference100 articles.

1. Atherosclerosis