Local and large-scale beta oscillatory dysfunction in males with mild traumatic brain injury-Reference-Cited by-同舟云学术

Local and large-scale beta oscillatory dysfunction in males with mild traumatic brain injury

Published:2020-12-01 Issue:6 Volume:124 Page:1948-1958
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Zhang Jing¹²,Safar Kristina¹²,Emami Zahra¹²,Ibrahim George M.²³⁴⁵,Scratch Shannon E.⁶⁷⁸⁹,da Costa Leodante³¹⁰,Dunkley Benjamin T.¹²¹¹

Affiliation:

1. Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, Ontario, Canada

2. Neurosciences & Mental Health, SickKids Research Institute, Toronto Ontario, Canada

3. Department of Surgery, University of Toronto, Toronto, Ontario, Canada

4. Institute for Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

5. Department of Neurosurgery, Hospital for Sick Children, Toronto, Ontario, Canada

6. Bloorview Research Institute, Toronto, Ontario, Canada

7. Holland Bloorview Rehabilitation Hospital, Toronto, Ontario, Canada

8. Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada

9. Rehabilitation Sciences Institute, University of Toronto, Toronto, Ontario, Canada

10. Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

11. Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada

Abstract

Mild traumatic brain injury (mTBI) disrupts the dynamic repertoire of neural oscillations, but so far beta activity has not been studied. In mTBI, we found reductions in frontal beta and large-scale beta networks, indicative of thalamocortical dysconnectivity and disrupted information flow through cortico-basal ganglia-thalamic circuits. Relatively, connectivity more accurately classifies individual mTBI cases compared with regional power. We show the relevance of beta oscillations in mTBI and the reliability of these markers in classification.

Funder

Defence Research and Development Canada

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00333.2020

Reference61 articles.

1. Mild traumatic brain injury: Pathophysiology, natural history, and clinical management

2. Corticothalamic feedback and sensory processing

3. Reconfiguration of dominant coupling modes in mild traumatic brain injury mediated by δ-band activity: A resting state MEG study