Interhemispheric interactions between the right angular gyrus and the left motor cortex: a transcranial magnetic stimulation study-Reference-Cited by-同舟云学术

Interhemispheric interactions between the right angular gyrus and the left motor cortex: a transcranial magnetic stimulation study

Published:2021-04-01 Issue:4 Volume:125 Page:1236-1250
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Baarbé Julianne¹²,Vesia Michael¹²,Brown Matt J. N.¹²³,Lizarraga Karlo J.¹²⁴^ORCID,Gunraj Carolyn¹²,Jegatheeswaran Gaayathiri¹²,Drummond Neil M.¹²^ORCID,Rinchon Cricia¹²^ORCID,Weissbach Anne¹²⁵,Saravanamuttu James¹²,Chen Robert¹²^ORCID

Affiliation:

1. Department of Medicine, University of Toronto, Toronto, Ontario, Canada

2. School of Kinesiology, Brain Behavior Laboratory, University of Michigan, Ann Arbor, Michigan

3. Department of Kinesiology, California State University, Sacramento, California

4. Motor Physiology and Neuromodulation Program, Division of Movement Disorders and Center for Health + Technology, Department of Neurology, University of Rochester, Rochester, New York

5. Institute of Systems Motor Science, University of Lübeck, Lübeck, Germany

Abstract

Goal-directed hand movements rely on the right and left angular gyri (RAG and LAG) and motor cortex (M1), yet how these brain areas functionally interact is unclear. Here, we show that RAG stimulation facilitated right hand motor output from the left M1 but inhibited indirect (I)-waves in M1. Combined RAG and LAG stimulation increased GABAB, but not GABAA, receptor-mediated inhibition in left M1. These findings highlight unique brain interactions between the RAG and left M1.

Funder

Queen Elizabeth II Graduate Scholarship in Science & Technology

German Research Foundation

Dystonia Medical Research Foundation

Else Kröner-Fresenius-Stiftung

Gouvernement du Canada | Canadian Institutes of Health Research

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Parkinson Canada

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience