Alterations in gastrointestinal motility assessed by high-resolution antroduodenal manometry in patients with severe disorders of gut-brain interaction-Reference-Cited by-同舟云学术

Alterations in gastrointestinal motility assessed by high-resolution antroduodenal manometry in patients with severe disorders of gut-brain interaction

Published:2024-08-01 Issue:2 Volume:327 Page:G306-G315
ISSN:0193-1857
Container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology
language:en
Short-container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology

Author:

Soliman Heithem¹²^ORCID,Wuestenberghs Fabien¹³^ORCID,Desprez Charlotte¹^ORCID,Leroi Anne-Marie⁴,Melchior Chloé⁵^ORCID,Gourcerol Guillaume⁴^ORCID

Affiliation:

1. Department of Physiology, “Nutrition, inflammation and microbiota–gut–brain axis”, Université Rouen Normandie, INSERM, CHU Rouen, Rouen, France

2. Department of Gastroenterology, Hôpital Louis Mourier, AP-HP Nord, Université de Paris-Cité, Colombes, France

3. Department of Gastroenterology, Hôpital Avicenne, AP-HP, Sorbonne Paris Nord University, Bobigny, France

4. Department of Physiology, “Nutrition, inflammation and microbiota–gut–brain axis”, CHU Rouen, Université Rouen Normandie, INSERM, ADEN UMR1073, CIC-CRB 1404, Rouen, France

5. Department of Gastroenterology, “Nutrition, inflammation and microbiota–gut–brain axis”, Université Rouen Normandie, INSERM, ADEN UMR1073, CHU Rouen, CIC-CRB 1404, Rouen, France

Abstract

Gastrointestinal dysmotility has been assessed poorly in disorders of gut-brain interaction (DGBI), especially with high-resolution antroduodenal manometry. Plots of DGBI patients showed lower duodenal contractions during phase II regarding amplitude, frequency, and contractile integral/sensor (CI/s) compared with healthy volunteers. A lower frequency of propagated antroduodenal contractions was also reported. Finally, antral CI/s was lower in patients with functional dyspepsia during phase III. Further studies are needed to assess the clinical significance of these alterations.

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpgi.00039.2024

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