Patients with autoimmune liver disease have glucose disturbances that mechanistically differ from steatotic liver disease-Reference-Cited by-同舟云学术

Patients with autoimmune liver disease have glucose disturbances that mechanistically differ from steatotic liver disease

Published:2024-06-01 Issue:6 Volume:326 Page:G736-G746
ISSN:0193-1857
Container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology
language:en
Short-container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology

Author:

Jensen Anne-Sofie H.¹²³^ORCID,Ytting Henriette¹⁴^ORCID,Werge Mikkel P.¹^ORCID,Rashu Elias B.¹^ORCID,Hetland Liv E.¹^ORCID,Thing Mira¹^ORCID,Nabilou Puria¹^ORCID,Burisch Johan¹⁴^ORCID,Bojsen-Møller Kirstine N.⁴⁵^ORCID,Junker Anders E.¹,Hobolth Lise¹^ORCID,Mortensen Christian¹,Tofteng Flemming¹,Bendtsen Flemming¹⁴^ORCID,Møller Søren⁴⁶^ORCID,Vyberg Mogens⁷⁸,Serizawa Reza R.⁷^ORCID,Gluud Lise L.¹⁴^ORCID,Wewer Albrechtsen Nicolai J.²³^ORCID

Affiliation:

1. Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark

2. Department of Clinical Biochemistry, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark

3. Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

4. Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

5. Department of Endocrinology, Copenhagen University Hospital–Amager and Hvidovre Hospital, Hvidovre, Denmark

6. Department of Clinical Physiology and Nuclear Medicine, Center for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark

7. Department of Pathology, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark

8. Department of Clinical Medicine, Center for RNA Medicine, Aalborg University, Copenhagen, Denmark

Abstract

Patients with autoimmune liver disease but without overt diabetes display glucose disturbances early on in their disease course. We identified pathophysiological traits specific to these patients including altered incretin responses.

Funder

European Foundation for the Study of Diabetes

Novo Nordisk Fonden

Sundhed og Sygdom, Det Frie Forskningsråd

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpgi.00047.2024

Reference59 articles.

1. Regulation of hepatic glucose metabolism in health and disease

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3. Prevalence of diabetes in liver cirrhosis: A systematic review and meta‐analysis

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