Affiliation:
1. Department of Transplantation and Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida
Abstract
Extracellular vesicles (EVs) are membrane-bound vesicles that are released by cells into their extracellular environment, have selective enrichment of specific proteins and RNA, and can mediate intercellular communication. In this review we highlight recent observations of the role of EVs in liver injury, viral hepatitis, alcoholic or nonalcoholic liver disease, biliary tract disease, and liver cancers. Potential applications as markers of diseases or for therapeutic applications are outlined to emphasize the new opportunities that are arising from the study of EVs.
Funder
HHS | NIH | NIH Office of the Director (OD)
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Publisher
American Physiological Society
Subject
Physiology (medical),Gastroenterology,Hepatology,Physiology
Cited by
46 articles.
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