Adiponectin affects ileal contractility of mouse preparations-Reference-Cited by-同舟云学术

Adiponectin affects ileal contractility of mouse preparations

Published:2024-02-01 Issue:2 Volume:326 Page:G187-G194
ISSN:0193-1857
Container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology
language:en
Short-container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology

Author:

Idrizaj Eglantina¹^ORCID,Nistri Silvia²^ORCID,Nardini Patrizia²^ORCID,Baccari Maria Caterina¹^ORCID

Affiliation:

1. Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Firenze, Italy

2. Department of Experimental and Clinical Medicine, Imaging Platform, University of Florence, Firenze, Italy

Abstract

This study provides the first evidence that adiponectin (ADPN) is able to act on ileal preparations. Functional results demonstrate that the hormone, other than causing a slight decay of the basal tension, depresses the amplitude of both spontaneous contractility and neurally induced excitatory responses of the mouse ileum through the involvement of nitric oxide. The expression of the ADPN receptor AdipoR1 and its localization on glial cells was revealed by Western blot and immunofluorescence analysis.

Funder

Università degli Studi di Firenze

Publisher

American Physiological Society

Subject

Physiology (medical),Gastroenterology,Hepatology,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpgi.00203.2023

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