Transcutaneous auricular vagal nerve stimulation improves functional dyspepsia by enhancing vagal efferent activity

Author:

Zhu Ying12ORCID,Xu Feng3,Lu Dewen3,Rong Peijing4,Cheng Jiafei5ORCID,Li Miaomiao6,Gong Yaoyao2,Sun Chao1,Wei Wei7,Lin Lin2,Chen Jiande D. Z.8

Affiliation:

1. Division of Gastroenterology, Northern Jiangsu People’s Hospital, Yangzhou, China

2. Division of Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China

3. Division of Gastroenterology, Yinzhou Hospital Affiliated to Medical School of Ningbo University, Ningbo, China

4. Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China

5. Division of Gastroenterology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China

6. Division of Gastroenterology, the Affiliated Huaian No. 1 People’s Hospital of Nanjing Medical University, Huaian, China

7. Division of Gastroenterology, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, China

8. Division of Gastroenterology and Hepatology, School of Medicine, University of Michigan, Ann Arbor, Michigan

Abstract

Treatment of functional dyspepsia is difficult due to various pathophysiological factors. The proposed method of transcutaneous auricular vagal nerve stimulation improves symptoms of both dyspepsia and depression/anxiety, and gastric functions (accommodation and slow waves), possibly mediated via the enhancement of vagal efferent activity. This noninvasive and easy-to-implement neuromodulation method will be well received by patients and healthcare providers.

Funder

Chinese Medicine Technology Project of Zhejiang Province

Publisher

American Physiological Society

Subject

Physiology (medical),Gastroenterology,Hepatology,Physiology

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