Measurement of low-grade inflammation of the esophageal mucosa with electrical conductivity shows promise in assessing PPI responsiveness in patients with GERD-Reference-Cited by-同舟云学术

Measurement of low-grade inflammation of the esophageal mucosa with electrical conductivity shows promise in assessing PPI responsiveness in patients with GERD

Published:2021-07-01 Issue:1 Volume:321 Page:G29-G40
ISSN:0193-1857
Container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology
language:en
Short-container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology

Author:

Manabe Noriaki¹^ORCID,Yamamoto Takatoki²,Matsusaki Michiya³,Akashi Mitsuru⁴,Haruma Ken⁵

Affiliation:

1. Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School, Okayama, Japan

2. Department of Mechanical and Control Engineering, Graduate School of Engineering, Tokyo Institute of Technology, Tokyo, Japan

3. Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Osaka, Japan

4. Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

5. Department of General Internal Medicine 2, Kawasaki Medical School, Okayama, Japan

Abstract

Bioelectrical admittance measurement is a new method to evaluate esophageal mucosal permeability vertically during upper gastrointestinal endoscopy. Measurement of low-grade inflammation of the esophageal mucosa with electrical conductivity shows promise in assessing proton pump inhibitor responsiveness in patients with gastroesophageal reflux disease. As various gastrointestinal diseases are associated with changes in mucosal permeability, bioelectrical admittance measurement is expected to be clinically applied to therapeutic decision-making for these diseases in the future.

Funder

Japan Society for the Promotion of Science KAKENHI

Publisher

American Physiological Society

Subject

Physiology (medical),Gastroenterology,Hepatology,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpgi.00365.2020

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